Tumor Necrosis Factor Inhibitor Drugs Market Worth $42.1 Billion By 2026

The global tumor necrosis factor inhibitor drugs market size is anticipated to reach USD 42.1 billion by 2026, according to a report published by Grand View Research, Inc. Increasing prevalence of autoimmune diseases, rapid technological advancements, and rise in healthcare expenditure across the globe are some of the major factors expected to drive the growth.

Currently, there are five approved TNF inhibitor drugs in the market- Humira (adalimumab), Enbrel (etanercept), Remicade (infliximab), Simponi/Simponi Aria (golimumab), and Cimzia (certolizumab). Biosimilar versions of Humira, Enbrel, and Remicade have been launched, causing a significant paradigm shift in the market.

The wave of biosimilars pose a significant internal threat to the biologics sale as biosimilars have a comparable efficiency as the original products. The cost-effectiveness of biosimilars makes them an attractive choice in economically sensitive areas. In addition, emerging countries, such as India, China, and South Korea are active participants in the biosimilar market.

Some of the key therapeutic areas involving treatment with TNF inhibitor drugs are rheumatoid arthritis, psoriasis, psoriatic arthritis, Crohn’s disease, and ulcerative colitis. Although these medicines are mostly used for the treatment of autoimmune diseases, several ongoing studies are investigating the role of TNF inhibitors in the treatment of cancer and other inflammatory conditions.

Some of the key players in the TNF inhibitor space are involved in strategic initiatives, such as mergers and acquisitions and joint ventures for the co-development of products. In addition, patent infringement issues between the manufacturers makes the market dynamics intensely competitive. For instance, AbbVie resolved an issue with Boehringer Ingelheim, regarding Humira’s intellectual property (IP) rights. As per the terms of the agreement, Boehringer Ingelheim received a non-exclusive license to Humira’s IP in the U.S.- scheduled to begin in July 2023.

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https://www.grandviewresearch.com/industry-analysis/tumor-necrosis-factor-tnf-inhibitor-drugs-market

Further key findings from the study suggest:

Humira accounted for nearly half the revenue share of TNF inhibitor drugs market in 2018
Emergence of biosimilars is anticipated to be the major growth rendering driver for the market
Psoriasis is projected to be the most rapidly growing application segment over the forecast period
Increased adoption of e-commerce is a key driver for online pharmacies
TNF inhibitors faces an external threat from IL-inhibitors

Civil Engineering Market Worth $13.35 Trillion By 2027

The global civil engineering market size is expected to reach USD 13.35 trillion by 2027, according to a new report by Grand View Research Inc. It is projected to exhibit a CAGR of 5.4% during the forecast period. Rising public-private partnership to aid the investment in infrastructure development in emerging economies is expected to bolster the growth.

Increasing adoption of advanced technologies and digitalization is expected to have positive impact on sustainable development of civil engineering value chain across the globe. These trends are expected to strengthen the network of players in the construction value chain and facilitate the digital transformation process, thereby driving the market for civil engineering.

Numerous market players are focusing on the use of green building products owing to the rising significance of eco-friendly products and energy efficiency. Thus, the shift of construction sector from the use conventional construction materials, is expected to heighten of importance of civil engineering for the successful execution of construction projects.

The government, private contractors, and public-private partnerships are the major buyers of civil engineering services for the development of residential and commercial projects, infrastructure projects, and industrial facilities. Rapid rise in service standardization and establishment of regulatory norms among major economies is anticipated to positively influence the market growth.

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https://www.grandviewresearch.com/industry-analysis/civil-engineering-market

Further key findings from the report suggest:

Planning & Design service segment is expected to expand at a CAGR of 6.1% over the estimation period owing to its rising significance in mega construction projects involving enormous capital investment for efficient and cost-effective operations
In 2019, real estate applications held the dominant market share of 41.9% on account of burgeoning demand for single family dwellings and multistoried apartments for rapidly rising population
The revenue from government sector stood at USD 3.63 trillion in 2019 and is projected to expand at a CAGR of 5.3% over the forecast period on account of rising government investments in infrastructure building in emerging economies
Asia Pacific accounted for a revenue share of 32.5% in 2019 and is anticipated to continue this trend over the forecast period, owing to rapid expansion of real estate sector along with infrastructure development in emerging economies, such as India and China

Dental Chair Market Size Worth $639.4 Million By 2026

The global dental chair market is expected to reach USD 639.4 million by 2026, according to a new report by Grand View Research, Inc., exhibiting a CAGR of 4%. Dental chairs are vital for any dental procedure. Rising need for comfortable chairs during surgeries and increasing demand for dental aesthetics are expected to boost growth during the forecast period. Therefore, key players are increasingly focusing on patient comfort while designing these chairs. Technological advancements such as addition of imaging systems, operating lights, footswitches, extended trays, and x-ray viewers have led to the introduction of innovative designs, thereby creating growth opportunities for market players.

Advancements in infrastructure in the healthcare and medical industry are expected to propel dental chair market growth. Moreover, increasing prevalence of oral diseases & dental disorders worldwide due to unhealthy eating habits, high sugar in daily diet, smoking, family history, and infections, such as AIDS or HIV, is boosting the demand for various dental equipment. This, in turn, is fueling the demand for dental examinations, thereby driving overall growth.

North America held the largest share in 2018 owing to factors such as high prevalence of dental disorders, growth in geriatric population, and improvement in infrastructure. Besides periodontal diseases, other common dental diseases prevalent in North America are tooth decay, bad breath, tooth erosion, and sensitivity, among others.

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https://www.grandviewresearch.com/industry-analysis/dental-chair-market

Further key findings from the report suggest:

The powered chairs segment held the largest share in 2018 and is expected to grow at a considerable rate during the forecast period
Increasing number of innovations and growing preference by dental surgeons can be attributed to the high share of this segment
Ceiling mounted design held a significant share of the market in 2018 as this design offers better assistance to dentists in performing multiple surgeries
Among all applications, examination held the largest share owing to increasing awareness about oral benefits and rising incidence of several dental diseases
Asia Pacific is expected to grow at a significant rate during the forecast period due to rising number of campaigns & initiatives by several organizations to create awareness about optimal dental health & hygiene and growing number of upgrades.

Dental Cement Market Size Worth $2.3 Billion By 2026

The global dental cement market size is expected to reach USD 2.3 billion by the end of 2026, according to a new report by Grand View Research, Inc., growing at CAGR of 6.3%. Increasing incidence of dental cavities & other dental diseases and introduction of new formulations are major drivers of the market.

Unhealthy eating & drinking habits, plaque formation, poor oral hygiene, fluoride deficiency, and disorders such as heartburn & dry mouth are some of the major predisposing factors. These factors have resulted in an increase in the number of dental procedures. For instance, according to an article published by PubMed, individuals who consume one sugary drink occasionally are at an increased risk of dental caries and tooth loss by nearly 44% as compared to ones who do not consume any.

Moreover, advancements in these cements and material technology have led to introduction of more durable and stronger cements, fueling growth. For instance, resin-modified ionomer cement demonstrated improved adhesion, higher tensile strength, and reduced post-cementation sensitivity when compared to conventional glass ionomer.

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https://www.grandviewresearch.com/industry-analysis/dental-cement-market

Further key findings from the report suggest:

Resin-based segment is anticipated to grow considerably over the forecast period, due to increasing popularity of self-adhesive resin cements that have wide range of.
Rising adoption of cosmetic dental procedures has resulted in increased demand for tooth colored restorations by patients, thus indirectly boosting market demand for resin cement.
Relatively high disposable income in developed economies is one of the major reasons for the growing demand for cosmetic dental procedures
Glass ionomer held a substantial market share in 2018. This can be attributed to the fluoride release and recharging abilities of this cement, aiding prevention of dental caries
The permanent segment is expected to lead in the coming years owing to features such as better aesthetics, excellent resistance, good compatibility with dental tissues, and insolubility in oral fluids or saliva
Restoration segment is anticipated to grow substantially in the future due to the growing number of ceramic restorations procedures
North America held a dominant share of the dental cement market due to well-established medical facilities, presence of skilled professionals, and extensive research activities
Some of the key players are 3M Company; Ivoclar Vivadent AG; Dentsply Sirona; Danaher Corporation; SHOFU Dental GmbH; BISCO, Inc.; and Medental International, Inc.

Intelligent Transportation System Market Worth $37.64 Billion By 2027

The global intelligent transportation system market size is expected to reach USD 37.64 billion by 2027, exhibiting a CAGR of 5.8% over the forecast period, according to a study conducted by Grand View Research, Inc. Necessity to reduce traffic congestion and improve road safety and security, implementation of data analytics and cloud computing in traffic management systems, and cost-effectiveness of intelligent transportation systems is projected to fuel the market growth.

Rapidly changing consumer demand has subsequently posed new challenges for manufacturers and retailers. Consumers are particularly demanding for reliability and efficiency, same-day deliveries, and real-time shipment tracking facilities. Timely delivery owing to reduce in-transit time and tracking facility are some of the features that are particularly in demand. Provisioning these features would require a comprehensive transportation management system capable enough of bridging the gap between order management and warehouse fulfillment. As a result, ITS vendors are introducing the latest solutions that can effectively meet the challenges posed by the growth of the e-commerce industry and the changing consumer behavior.

In addition to being one of the leading causes of accidents, lack of road safety also results in high costs and adversely impacts the overall economic development. Numerous initiatives are being undertaken to install technologically advanced traffic management systems and overall awareness about the importance of road security and safety. This is expected to result in the demand for Vehicle-to-Vehicle (V2V) and Vehicle to Infrastructure (V2I) over the forecast period. Developed markets of Europe and North America have mandated the use of Electronic Stability control (ESC) systems, a driver assistance system, and in passenger as well as commercial vehicles. This is expected to favorably impact the overall demand for intelligent transportation system over the forecast period.

Moreover, in 2020, the ITS market will be hampered due to the COVID-19 crisis, which has impacted demand, interrupted production, and disrupted supply chain. Thus, various market players are experiencing flat or lower unit sales. However, with economic stimulus packages announced by many countries such as Japan, U.S., China, France, Italy, India, U.K., and Germany, is anticipated to create great opportunities for transportation infrastructure development.

North America ITS market dominated in 2019 and is projected to continue its dominance over the foreseen years. The U.S. alone holds more than 75% of the market share in North America. The U.S. government has developed a national architecture that offers guidance to private companies and urban areas likely to implement an intelligent transportation system of what functions and communication technologies are essential to be compatible with other systems. This architecture is specifically aimed at providing interoperability for ITS across U.S. Moreover, strong government support, R&D activities, and strategic public-private partnerships aimed at improving the transportation network across the region are some major factors fueling the growth of the market for intelligent transportation system.

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https://www.grandviewresearch.com/industry-analysis/intelligent-transportation-systems-industry

Further key findings from the study suggest:

The Advanced Traffic Management System segment is expected to dominate the ITS market owing to it helps in detecting dangerous weather conditions, roadway hazards, accidents, and creates a complete integrated view of overall traffic flow. The segment is expected to reach USD 12.16 billion by 2027
The traffic management market is expected to dominate the application segment and the trend is expected to continue over the forecast period. It is anticipated to reach USD 12.07 billion by 2027. Traffic management systems help enhance operational performance and reliability of road networks
North America is projected to account for the majority share of the market over the forecast period. Advancements in communication technologies are boosting the revolution of the transportation network in U.S. The region is anticipated to reach USD 14.33 billion by 2027

Advanced Bipolar Direct Energy Devices Market Worth $3.3 Billion By 2026

The global advanced bipolar direct energy devices market size is anticipated to reach USD 3.3 billion by 2026 registering a CAGR of 14.2%, according to a new report by Grand View Research, Inc. Increasing adoption of bipolar electrosurgical systems over conventional devices and high demand for laparoscopic surgeries are anticipated to boost the market growth.

These systems are mostly used to coagulate, cutting, fulguration, and desiccate soft tissues through generating heat by an electric current. The product demand has been increasing owing to its benefits in surgical procedures, such as lower risk of hemorrhaging than conventional devices that focus on scalpels. In addition, conventional equipment are costlier, which is also driving the demand for advanced bipolar direct energy systems for improved safety in desiccating soft tissues.

Technological advancements in the field are further expected to augment the market growth. For instance, XCELLANCE Medical Technologies launched a new 6-sense technology designed for cutting tissues at lower voltages by sensing voltage and power. This technology minimizes the patient recovery time and is a versatile tool for hemostatic dissection in performing surgical procedure.

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https://www.grandviewresearch.com/industry-analysis/advanced-bipolar-direct-energy-devices-market

Further key findings from the report suggest:

Electrosurgical generator systems led the global market in 2018. The segment is projected to expand further at the fastest CAGR from 2019 to 2026
Hospital was the dominant end use segment in 2018 owing to increased number of laparoscopic surgical procedures for tissue coagulation performed in these healthcare settings
North America led the global advanced bipolar direct energy devices market in 2018. However, Asia Pacific is estimated to be the fastest-growing regional market over the forecast period
Some of the key companies in this market are Bovie Medical Corp., Medtronic PLC, B. Braun Melsungen AG, XCELLANCE Medical Technologies Pvt. Ltd., Olympus Corp., and Karl Storz
These companies focus on technological advancements to gain competitive advantage. Medtronic launched Aquamantys bipolar sealers designed by transcollation technology, which combines Radiofrequency (RF) energy and saline to provide hemostatic sealing of soft tissues

Scleroderma Therapeutics Market Size Worth $2.6 Billion By 2026

The global scleroderma therapeutics market size is expected to reach over USD 2.6 billion by 2026 registering a CAGR of 6.0%, according to a new study by Grand View Research, Inc. The market growth is credited to the availability of various therapies used off-label, such as small molecule therapies including branded, generics, and OTC drugs.

The mix of several indications and drug classes engenders a fragmented market with multiple players. Roche is the dominant company with biologic immunosuppressants, Actemra/RoActemra, Cellcept, and Rituxan contributing majorly to the company’s share. Pfizer and Eli Lilly are the key companies in the market. Over the forecast period, new entrants including Boehringer Ingelheim, Corbus Pharmaceuticals, and Fibrocell will marginally displace the share of established firms in this market.

The on-label market is in the development phase. Supplemental indication approval is one of the most common strategies adopted by market participants. For example, riociguat by Bayer was previously used for PAH and currently, it is under clinical trials for the treatment of SSc-related digital ulcers. There are several other pharmaceutical companies following suit as this strategy favors the pharmaceutical industry in offsetting high development costs and in reaping larger benefits from one molecule already developed and present in the market.

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https://www.grandviewresearch.com/industry-analysis/scleroderma-therapeutics-market

Further key findings from the study suggest:

The immunosuppressants segment held the largest market share in 2018 and is likely to maintain the dominance throughout the forecast years
High preference for immunosuppressants owing to the favorable reimbursement scenario associated with this drug class supports its dominant market share
Systemic scleroderma indication segment accounted for the major market share and will expand further due to use of high-priced immunosuppressants
U.S. held the majority of the share in 2018. Expected label expansions and expected launch of first-in-class therapies coupled with an evolving reimbursement landscape for orphan drugs support continual scleroderma therapeutics market growth
Europe trails with a lower share as compared to the U.S. majorly due to higher use of generics and biosimilars for off-label treatment of scleroderma
Some of the key companies are F. Hoffman La-Roche Ltd.; Bristol-Myers Squibb Company; Celgene Corp.; arGentis Pharmaceuticals, LLC; Bayer AG; Boehringer Ingelheim International GmbH; Akashi Therapeutics; Prometic Life Sciences, Inc.; Emerald Health Pharmaceuticals; Kadmon Holdings, Inc.; Seattle Genetics, Inc.; Cytori Therapeutics, Inc.; Fibrocell Science, Inc.; Chemomab; Corbus Pharmaceuticals Holdings, Inc.; and Genkyotex SA

Oral Irrigator Market Size Worth $1.1 Billion By 2026

The global oral irrigator market size is expected to reach USD 1.1 billion by 2026, according to a new report by Grand View Research, Inc., registering a 3.4% CAGR during the forecast period. Introduction of technologically advanced dental care products and growing incidence of oral diseases, such as dental caries and periodontitis, are majorly driving the market.

Easy availability of oral irrigators for end users like dentists and consumers is one of the drivers of the global oral irrigator market. These are available through various online portals such as Amazon, eBay, and AliExpress, and medical stores.

Initiatives by various dental organizations and agencies, especially in developing countries such as India, are significantly impacting market growth. In India, agencies such as eDantSeva, National Tobacco Control Programme (NTCP) and National Institute of Cancer Prevention and Research (NICPR) conduct programs for increasing awareness regarding dental hygiene and habits, further propelling the market.

Oral irrigators are expensive as compared to traditional floss products, which is hampering oral irrigator market growth. Nonetheless, value benefits offered by manufacturers for the promotion of technologically advanced products, along with increasing pricing competition, is estimated to lower the impact of high costs and increase its popularity among consumers. This is likely to help shift individual preference from tradition flossing methods to using efficient oral irrigators.

Click the link below:
https://www.grandviewresearch.com/industry-analysis/oral-irrigator-market

Further key findings from the study suggest:

Cordless product variants formed the leading segment owing to features such as safety, portability, and reasonably priced. The countertop segment is also likely to witness steady growth owing to convenience as they do not require charging like cordless devices
Product adoption for home use has been on a rise owing to increasing popularity of technologically advanced products and growing awareness regarding benefits of regular flossing and good dental hygiene
Increasing prevalence of teeth and gum disorders on a global scale, rise in population in developing economies, and increase in spending power of consumers are anticipated to majorly drive the oral irrigator market
Some of the key players in the market are Church & Dwight Co., Procter & Gamble, Jetpik, Aquapick, and Conair Corporation.

Wound Care Market Size Worth $25.1 Billion By 2026

The global wound care market size is expected to reach USD 25.1 billion by 2026, according to a new report by Grand View Research, Inc., registering a 3.9% CAGR during the forecast period. Increase in prevalence of chronic diseases globally, rising number of ambulatory surgical centers (ASCs), and growing geriatric population are key factors driving the global market.

ASCs offer a variety of services such as surgical assistance, diagnostics, and preventive procedures. Surgeries for pain management, urology, orthopedics, restorative, and gastro intestinal (GI) conditions are also performed in ambulatory surgery centers. Earlier, ASCs were only capable of performing GI-related minor surgeries; however, with increase in number of minimally invasive surgical procedures, services offered by ambulatory surgical centers have expanded and grown exponentially.

According to the U.S. Department of Health and Human Services (HHS) data records of 2014, there were 17.2 million hospital visits. These included invasive, therapeutic surgeries, and ambulatory surgeries. Around 9.94 million (57.8%) of these surgeries occurred in hospital-owned ambulatory surgery settings and the remaining 7.26 million surgeries (42.2%) were conducted in hospitals. ASCs are increasing in number and thus offer cost-effective services. In addition, favorable reimbursement coverages are being provided with regard to services provided by ASCs. The chances of contracting post-surgical, hospital-related infections are also reduced. ASCs provide specific instructions to patients regarding post-surgical homecare. Thus, with an increase in the number of ASCs and number of surgical procedures, demand for wound care is expected to increase.

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https://www.grandviewresearch.com/industry-analysis/wound-care-market

Further key findings from the report suggest:

In terms of revenue, the advanced dressing segment held the largest share in 2018 owing to increasing cases of chronic diseases and rising adoption of advanced wound care products across the globe
The home healthcare segment is expected to witness the fastest growth over the forecast period due to increasing geriatric population and rising adoption of negative pressure wound therapy
On the basis of application, the acute segment held the largest wound care market share in 2018 owing to rising number of surgeries and burn cases across the globe
Asia Pacific is expected to witness the fastest growth over the forecast period owing to increasing number of surgeries and rising cases of burns in this region
Prominent key players present in the wound care market include Smith and Nephew; Molnlycke Health Care AB; and Baxter International Inc.

Breast Reconstruction Market Worth $3.8 Billion By 2026

The global breast reconstruction market size is expected to reach USD 3.8 billion by 2026, according to a new report by Grand View Research, Inc. It is projected to expand at a CAGR of 6.9% during the forecast period. Rising prevalence of breast cancer, cases of breast reconstruction procedures, and introduction of technologically advanced products are the key driving factors for the growth.

Increasing incidence of breast cancer across the globe is one of the key driving factors for the market growth. According to the Breast Cancer Research Foundation (BCRF), breast cancer is considered as the most common type of cancer among American women after skin cancer. Such high incidence in U.S. has resulted in an increased number of mastectomy and lumpectomy procedures, which boosts the demand for breast implants and tissue expanders.

According to the American Cancer Society, Cancer Facts & Figures 2015, BCRF also estimated that over 40,290 women may die due to breast cancer. Prevention of breast cancer involves mastectomy, which requires removal of the entire organ. Breast reconstruction helps restore the shape of the breast, thereby enhancing the quality of a patient’s life. It basically involves rebuilding the shape of the removed breast. Thus, high prevalence of breast cancer and growing number of mastectomies are the major factors anticipated to drive the demand for breast reconstruction procedures, thereby propelling the market growth over the forecast period.

Click the link below:
https://www.grandviewresearch.com/industry-analysis/breast-reconstruction-market

Further key findings from the report suggest:

In terms of revenue, breast implants segment held the largest market share in 2018 and is expected to witness the fastest CAGR over the forecast period owing to the rising consciousness towards physical appearance and increasing disposable income in the developed and developing countries
Anatomical breast implants is expected to witness the fastest CAGR over the forecast period owing to the increasing incidence of breast cancer across the globe
Hospital segment held the largest market share in 2018 due to the rising cases of breast reconstruction surgeries
Asia Pacific breast reconstruction market is expected to witness the fastest CAGR over the forecast period owing to the rising number of surgical procedures in this region
Prominent market players are Mentor Worldwide LLC; Allergan Inc.; Sientra, Inc.; Ideal Implant Incorporated; Establishment Labs S.A.; and POLYTECH Health & Aesthetics GmbH