Oncology Companion Diagnostic Market Worth $5.7 Billion By 2027

The global oncology companion diagnostic market size is expected to reach USD 5.7 billion by 2027, expanding at a CAGR of 12.7%, according to a new report by Grand View Research, Inc. Expanding access to important genomic information with the aid of companion diagnostics enables informed decision making for designing the targeted treatment approaches for their patients, thereby increasing demand for comprehensive genomic testing and oncology companion diagnostics.

The commercial launch of drugs including Gleevec (imatinib) and Herceptin (trastuzumab) that require Companion Diagnostics (CDx) testing before prescription has increased revenue generation in the oncology companion diagnostics field. This growth is expected to continue in the future owing to a substantial number of CDx associated oncology drugs in clinical trials. Apart from functioning as exclusive or inclusive tests for therapies, CDx also plays a crucial role during participant selection in clinical trials. This is because there is an increased potential for a novel drug candidate to show a better response rate if the patient has its biomarker target.

The economic incentives associated with the use of CDx have encouraged drug developers to combine their drugs with diagnostic tests. However, the diagnostic manufacturers face conflicting demands from payers/providers on one hand and drug manufacturers on the other hand. The regulatory bodies also have stringent policies to align the development timelines of diagnostics and drugs. Therefore, the diagnostic companies are expected to broaden their scope of CDx development instead of focusing on the attainment of a match between a single diagnostic with a specific drug.

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https://www.grandviewresearch.com/industry-analysis/oncology-companion-diagnostics-market

Further key findings from the study suggest:

  • The product segment held the largest market share in 2019 owing to increased adoption and usage rate of CDx tests
  • A significant increase in the approval rate of CDx and a rise in investments for co-development of drugs and their CDx is expected to increase the revenue generation in the product segment
  • Consumables occupied a major share of the product segment owing to the frequent use and purchase of media, buffers, reagents, and other consumables required for CDx assay
  • Immunohistochemistry (IHC) occupied a major portion of the technology segment owing to the benefits offered by IHC technology including cost and time effectiveness, the suitability of the technique for small tumor types, high adoption of IHC for routine oncology CDx, and low technological requirements associated with IHC
  • Presence of a substantial number of FDA approved IHC based CDx assays such as EGFR pharmDx Kits, ER/PR pharmDx Kits, HercepTest Kits, PD-L1 IHC 28-8 pharmDx, VENTANA PD-L1 (SP142) Assay, VENTANA ALK (D5F3) CDx Assay, and VENTANA ALK IHC assay is also expected to increase revenue generation within the IHC segment
  • The Non-Small Cell Lung Cancer (NSCLC) segment dominated the market in 2019 and is expected to maintain its dominance during the forecast period
  • NSCLC is a lung cancer subtype that accounts for approximately 84.0% of all cases of lung cancer. According to data published by the American Cancer Society (ACS), in 2020, around 228,820 new cases of lung cancer are projected to be diagnosed in the U.S.
  • The breast cancer and leukemia segments are expected to grow with substantial rates owing to a rise in the number of cancer cases
  • The hospital segment held the largest share in the market in 2019 and is expected to exhibit a considerable growth rate, owing to a rise in the number of cancer diagnostic tests in the hospitals
  • North America dominated the market in 2019 owing to the presence of a substantial number of players in this region, as well as the presence of a large number of FDA-approved CDx solutions in cancer therapeutics
  • Advancements in technologies and improvements in the economic condition are anticipated to drive the market at the fastest growth rate in the Asia Pacific
  • The presence of communities in Asian countries that are actively involved in monitoring and discovery of genetic biomarkers is expected to positively influence the market
  • The key players in the market are involved in mutually beneficial partnerships with global entities, including sponsors and diagnostic commercialization partners, which enables them to leverage their market potential globally.

D-dimer Testing Market Size Worth $1.7 Billion By 2027

The global D-dimer testing market size is expected to reach USD 1.7 billion by 2027, expanding at a CAGR of 4.3%, according to a new report by Grand View Research, Inc. Technological advancements in D-dimer testing have resulted in the development of a wide range of products that have allowed healthcare professionals to offer suitable emergency assistance to patients. The concept of automation in D-dimer testing has provided rapid, less labor-intensive, and user-friendly diagnostic strategies, which is expected to drive the market in the near future.

The commercially available assays often have differences in their antibody specificity as D-dimer antibodies also detect Fibrin Degradation Products (FDPs), leading to incorrect results. To address this issue, Advanced ImmunoChemical, Inc. has developed two monoclonal antibodies, which are used to design one-step immunoassay specific for both FDP and D-dimer. Thus, the development of improved immunoassays that equally detect all FDPs is expected to boost the market growth.

Extensive research for the determination of new D-dimer threshold values for a specific population set prevents the usage of Computed Tomography Pulmonary Angiography (CTPA). This is beneficial as the elimination of CTPA leads to low radiation exposure, which, in turn, increases the demand for the test. To demonstrate this, a group of researchers from Japan determined new elevated D-dimer threshold values for the diagnosis of pulmonary embolism in the Japanese population. Such studies are expected to favor market growth.

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https://www.grandviewresearch.com/industry-analysis/d-dimer-market

Further key findings from the report suggest:

  • Reagents and consumables accounted for the largest revenue share in 2019 owing to the wide availability and frequent usage of reagents in the market space
  • Presence of blocking agents that reduce the interferences from heterophilic antibodies to increase the efficiency of immunoassays boost the reagents and consumables segment
  • Shorter turnaround times, ease of use, and generation of gold-standard quality results are among the few factors that lead to a lucrative growth of point-of-care testing
  • Enzyme-linked Immunosorbent Assays (ELISA) held the largest revenue share because microplate ELISA is considered as a reference method due to its high sensitivity for coagulation markers
  • Deep Vein Thrombosis (DVT) dominated the revenue share in 2019 as this test is a reliable method and is used as a routine screening test for DVT
  • The hospitals’ segment accounted for the maximum revenue share in 2019
  • This is attributive to a rise in the rate of pulmonary embolism cases in hospitalized patients, which results in high adoption of the test in hospitals
  • Asia Pacific is expected to witness a lucrative CAGR due to a rise in the funding initiatives that support research studies related to the usage of these assays in various diseases
  • The National Natural Science Foundation of China and the Fundamental Research Funds for the Central Universities are among the few agencies involved in funding research studies in China
  • Key companies operating in the market have undertaken several growth initiatives to expand their product portfolio
  • For instance, in February 2019, HORIBA introduced the Yumizen D-Dimer reagent kit for measurement and reference exclusion testing for DVT and pulmonary embolism.

Apoptosis Assay Market Size Worth $7.5 Billion By 2027

The global apoptosis assay market size is expected to reach USD 7.5 billion by 2027, expanding at a CAGR of 7.6%, according to a new report by Grand View Research, Inc. Extensive research activities on expanding applications of drug-induced apoptosis assays have propelled the inclination of pharmaceutical manufacturers towards incorporating cell cycle products in the drug discovery and designing process.

The introduction of affordable and easy to perform kits that can be accommodated in complex experiments is expected to minimize the overhead costs of apoptosis experiments. Companies are providing highly precise reagents and lot-to-lot reproducibility in sample measurements.

Professionals at pharmaceutical companies are making use of cell-cycle inhibitors and Apoptosis-Inducing Factors (AIF)/ molecules to explore possible drug targets. Also, high demand for caspase activity assays along with Bcl-2 protein family across pharmaceutical companies for apoptosis detection has been observed in recent years. Biotechnology companies are enhancing quantification techniques to enable real-time monitoring of apoptotic cellular dynamics.

The presence of established guidelines and protocols for cell-potency assays has strengthened the development of efficient cell-death detection assays. Whereas, stringent regulations with respect to the approval of cell-potency assays are ensuring successful uptake of market products launched.

The flow cytometry segment dominated the market and accounted for the largest revenue share in 2019. This is attributed to the increasing adoption of the technique among researchers. It helps in finding the difference between intact mitochondria (healthy cells) and permeabilized mitochondria (cells undergoing death). The segment is anticipated to grow fast over the forecast period.

The pharmaceutical and biotechnology segment dominated the market in 2019 and is anticipated to continue its dominance over the forecast period. This is attributed to the rising incidence of cancer and neurodegenerative disorders. In addition, the growing significance of programmed cell death or apoptosis to treat chronic diseases is driving the segment growth.

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https://www.grandviewresearch.com/industry-analysis/apoptosis-market

Further key findings from the study suggest:

  • The kits segment dominated the market and accounted for a revenue share of around 50.0% owing to increasing investment by key market players
  • Increase in the demand for fluorochrome-labeled inhibitors of caspases has made reagents the fastest growing product segment in the market
  • Application of these inhibitors with other techniques is anticipated to enhance the apoptosis assessment, thereby driving segment growth
  • Owing to the wide adoption and easy availability of products, flow cytometry is estimated to account for a substantial share of approximately 35.0% in 2019
  • The increasing significance of continuous monitoring of programmed cell death across novel drug discoveries and development of advanced therapeutics is set to propel market growth
  • North America has dominated the market in terms of revenue share in 2019, and Asia Pacific is expected to witness the fastest growth in the coming years as a result of the expanding CRO landscape in the region
  • Key companies are competing in terms of a combination of products and services in order to maintain market share.

Active Wheelchair Market Size Worth $2.3 Billion By 2027

The global active wheelchair market size is expected to reach USD 2.3 billion by 2027, expanding at a CAGR of 4.4%, according to a new report by Grand View Research, Inc. Surge in the geriatric and disabled population along with the rising prevalence of chronic diseases in the geriatric population are some of the key factors propelling the market growth.

Aging usually reduces the ability to move and perform physical tasks to maintain independent functioning. The increasing geriatric population is likely to create more demand for active wheelchairs over the forecast period. Moreover, they are more prone to falls, which can cause fatal or non-fatal injuries. The Western Europe region has the highest fall-related incidence and mortality rates in aged people. As per a research article published by Injury Prevention, in 2017, around 11.7 million aged people sought medical attention due to an injury, of which 8.4 million were owing to fall-related injuries. An increasing number of elderly people and rising incidents of falls in the elderly are projected to drive demand for active wheelchairs during the forecast period.

The introduction of technologically advanced active wheelchairs is also expected to drive the market as it provides more comfort to the users. In addition, increasing government initiatives to support the elderly and disabled population is boosting the market. For instance, the U.S. government provides various disability services to its citizens such as insurance for short-term and long-term disability, financial assistance & support services for the disabled, and education & jobs for persons with disabilities. In 2017, the Government of India offered free eldercare assistive devices under RashtriyaVayoshriYojana (RVY) to senior citizens belonging to lower economic strata of the country.

Furthermore, favorable reimbursement policies for the purchase of active wheelchairs, rising incidence of accidents, increasing spending on healthcare infrastructure, and increasing obese population across the globe due to drastic changes in daily lifestyle are also anticipated to propel the growth of the market.

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https://www.grandviewresearch.com/industry-analysis/active-wheelchair-market

Further key findings from the report suggest:

  • The manual wheelchairs segment was the largest segment in 2019 owing to the low cost of the product and continuous technological advancement to meet the increasing demand in the emerging countries
  • The powered wheelchairs segment is expected to register higher CAGR over the forecast period owing to an increase in product demand especially in developed countries such as the U.S. and Germany
  • Cerebral Palsy was the largest indication segment in 2019 owing to the higher global prevalence of the condition and support offered by the active wheelchairs to the patient with cerebral palsy
  • Europe dominated the market in 2019 with a 33.5% revenue share due to an increase in healthcare expenditure and growing geriatric and disabled population in the region
  • Asia Pacific is expected to register a higher CAGR over the forecast period owing to rising awareness levels and increasing disposable income in the region.

Quality Management Software Market Size Worth $17.08 Billion By 2027

The global quality management software market size is estimated to reach USD $17.08 billion by 2027, registering a CAGR of 10.1% from 2020 to 2027, according to a new study by Grand View Research, Inc. Quality management software (QMS) is used to better manage and control quality concerns regarding performance, customer satisfaction, and competitiveness of the organization. This is done by controlling the processes as well as products for consistent quality assurance, reducing the quality gap between manufacturing practices and end-product expectations, tracking of deviations, and ensuring compliances. Moreover, owing to the increasing advancements in functionality of solutions with the help of artificial intelligence (AI) and machine learning (ML) tools, the market is anticipated witness rapid growth.

The QMS market is expected to witness tremendous growth due to the increasing demand for effective management of organizational processes and the need for meeting consumer expectations in a highly competitive market. Rapid technology advancements in IT and telecom as well as the automation of transportation and logistics industry are driving the market growth. QMS software offers numerous functionalities including handling of non-conformances, out of specification test results, calibration, ensuring compliance as well as a centralized system that ensures connection to organizations’ ERP and CRM systems. All these capabilities coupled with the reduction in the costs are energizing the adoption of quality management software across a wide range of industries.

The flexibility and mobility offered by quality management software in solutions such as document control and non-conformances’ issue resolving is driving the demand for QMS software. The increasing demand for cloud based QMS solutions due to implied scalability and accessibility is becoming increasingly popular among all industrial sectors. For instance, in July 2019, MasterControl launched a new solution named MasterControl Manufacturing Excellence to help organizations bridge the gap between smart manufacturing and operational excellence by automating the last mile of production.

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https://www.grandviewresearch.com/industry-analysis/quality-management-software-market           

Further key findings from the report suggest:

  • Document control segment is expected to witness phenomenal growth over the forecast period. Compliance to stringent quality standards, rigorous regulations passed by FDA and other global regulations are prime factors for adherence to quality document control processes by the industries worldwide
  • The cloud segment is likely to grow rapidly during the forecast period. The popularity of cloud technology among cost-sensitive customers and small and medium enterprises is anticipated to boost the adoption of cloud QMS solutions
  • The small and medium enterprise segment is predicted to and at the highest CAGR from 2020 to 2027. An increase in the number of providers and reduced costs of QMS solutions has pushed its adoption by SMEs. Moreover, the utility of QMS solutions has also helped in process optimization and reduction in overall product costs
  • The healthcare segment is likely to grow at a rapid pace during the forecast period, owing to rapid regulatory updates and innovation in medical devices vis-à-vis technology trends such as the IoT and analytics are likely to boost the utility of QMS solutions in the forthcoming years

Microwave Oven Market Worth $12.70 Billion By 2022

The global microwave oven market size is anticipated to reach USD 12.70 billion by 2022, according to a new report by Grand View Research, Inc., rising at a CAGR of 2.8% during the forecast period. Improving the standard of living of consumers, a growing number of nuclear families, and increasing demand for frozen and ready-to-eat food are some of the key factors stimulating market growth.

A growing number of working women and preoccupied schedules of people in urban cities are likely to fuel the demand for ovens. A large part of new households comprises working singles who prefer to dine out rather than setting up their kitchen. This may be a drawback for the residential appliance market. However, this trend is estimated to boost the culture of quick-service restaurants, cafes, and small eateries, which in turn will work in favor of the market.

Robust growth of the hospitality sector and rising catering contracts for large-scale functions, seminars, and other social gatherings are also expected to stir up the demand for commercial appliances over the forecast period. In the case of the residential application segment, the most significant driver is the changing lifestyles and food consumption preferences of people, with more consumers shifting towards ready-to-eat and frozen food.

Macroeconomic factors such as growing population, rising disposable income of consumers, and increasing awareness of different cooking media such as microwave oven, grills, and barbeques are projected to impact the market positively.

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https://www.grandviewresearch.com/industry-analysis/microwave-oven-market

Further key findings from the report suggest:

  • The convection segment is poised to account for half of the overall market value by 2022
  • The grill microwave oven market is anticipated to be valued at around USD 4.50 billion by 2022
  • In 2016, North America was the leading revenue contributor in the market, with a valuation of around USD 3.5 billion
  • The household application segment accounted for a larger revenue share in 2016 and is likely to expand at a CAGR of around 3.0% over the forecast period
  • The key players in the market include Robert Bosch GmbH, Haier Group Corporation, Hobart, Hamilton Beach, Middleby Corporation Company, Whirlpool Corporation, and Sharp Corporation.

Bearings Market Size Worth $186.1 Billion By 2025

The global bearings market size is expected to reach USD 186.1 billion by 2025, according to a new report by Grand View Research, Inc. It is projected to register a CAGR of 9.1% during the forecast period. Bearings are essential in almost every application that involves motion and they help minimize friction between different mechanical components in several industrial machinery and equipment, resulting in reduced energy consumption. Hence, this machine element finds application in all industries, ranging from automobiles, household appliances, and aerospace to industrial machinery, using machinery or related motor-driven linkages.

The bearings market is estimated to witness a considerable growth in the forthcoming years, ascribed to the aim to achieve energy efficiency. Energy saving and bearings go hand-in-hand. The main objective of this element is saving energy by reducing friction, be it during the rotation of shafts of a transmission or the wheel of a vehicle. Additionally, rising demand for commercial vehicles is expected to catapult the demand from automotive sector across the world.

Technological advancements including smart bearings, development of advanced materials and lubricants, and integrating sensor units, are anticipated to provide high growth potential to the market. With the objective of enhancing performance, vendors are incorporating sensor units of the product. Sensor units help digital monitoring of rotation speed, axial movement, load carrying capacity acceleration, and deceleration. These units are presently being used in conveyors forklifts, road rollers, and electric motors. Furthermore, the integration of IoT capabilities facilitates manufacturers to monitor bearing operations constantly.

The market is mature with a dynamic demand closely related to the state of engineering industries and capital goods. Companies are offering integrated products that significantly decrease the number of bearings that go into an assembled product and reduce the overall cost of equipment. This in turn is also increasing the shelf-life and reliability of the product. Product manufacturers are increasingly investing in R&D to address the intensifying competition by providing innovative products.

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https://www.grandviewresearch.com/industry-analysis/bearings-market

  • The development of cost-effective wind energy generating product has resulted in their increased espousal within wind turbine applications that aid in increasing energy production, reduce lubricant consumption, and enhancing turbine performance and reliability
  • Roller bearings is anticipated to emerge as the largest product segment by 2025 and outpace ball bearings, ascribed to their ability to carry heavy loads and shock or impact loading
  • Railway and aerospace segment is estimated to witness the fastest CAGR of over 8.0% over the foreseeable years, due to their growing demand in applications such as shock absorbers, gearboxes, doors, and tilting mechanisms to name a few
  • Asia Pacific is anticipated to witness the fastest CAGR of over 5.0% by 2025 attributed to the increased demand for fuel-efficient passenger vehicles, industrialization, and swift infrastructure development
  • The key competitors operating in the bearings market include SKF, NSK, Timken, Schaeffler, NTN, and JTEKT. Various leading companies are investing in high-level R&D to come up with innovative solutions. These solutions are focused on being cost-effective as well as on enhancing the overall quality of the end-product

GPS Market Size Worth $146.4 Billion By 2025

The global positioning systems (GPS) market size is anticipated to reach USD 146.4 billion by 2025, according to a new study by Grand View Research, Inc., exhibiting a CAGR of 18.4% during the forecast period. Burgeoning popularity of location-based services such as online food delivery and e-hailing services are projected to create significant demand for GPS-enabled devices over the forecast period. Furthermore, increasing use of GPS devices for navigation purposes in military aircraft and navy ships is poised to propel the market.

Global positioning systems are satellite-based navigation systems that provide real-time location of objects. GPS is widely used in a variety of civil applications, including road transportation, shipping, rail transportation, heavy vehicle guidance, surveying and mapping, social activities, and financial services. GPS transmitters use data to provide exact location of the object. Moreover, a GPS can work in any weather condition that makes it more versatile and reliable.

Among all application segments, the location-based services and road segments are expected to be significant revenue contributors in the global market during the forecast period owing to increasing deployment of GPS technology in smartphones, tablets, networking devices, IoT devices, and connected vehicles. Rising adoption of smartphones and growing consumer inclination towards digital services such as online retailing, cab services, and food at door steps are likely to spur the growth of the market during the forecast period.

In addition, increasing investments by large market players in developing countries such as China, India and Indonesia are expected to boost overall adoption through partnership with local suppliers. This will help the Asia Pacific market to gain traction over the coming years. However, lack of network infrastructure and  lack of awareness of GPS technology among large population are estimated to hinder the growth of the market over the forecast period.

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https://www.grandviewresearch.com/industry-analysis/gps-market

Further key findings from the study suggest:

  • North America accounted for the largest market share in 2017 followed by Europe, owing to a large number of smartphone users, high demand for GPS devices for connected fleets, and presence of key market players
  • The Asia Pacific GPS market is expected to witness significant growth over the forecast period on account of increasing per capita expenditure, growing economy, and high adoption of smartphones
  • The location-based services application segment accounted for over 41.0% of the global GPS market in 2017 owing to a surge in the demand for GPS devices for navigation and travel, retail and real estate searches, geo-social networking, and mobile marketing and advertising purposes
  • Prominent market players are focusing on undertaking mergers and acquisitions with system integrators to increase their overall revenue share. Additionally, key players are continually  investing in development of new products to gain a higher market share and increase their overall profitability
  • Military expenditure by governments of countries such as the U.S., Russia, China, India, and Saudi Arabia is projected to rise significantly, thus fueling the growth of the global GPS market over the forecast period.

Multiparameter Patient Monitoring Systems Market Worth $15.4 Billion By 2027

The global multiparameter patient monitoring systems market size is expected to reach USD 15.4 billion by 2027 registering a CAGR of 5.5%, according to a new report by Grand View Research, Inc. Rising health concerns and resultant need to constantly monitor the health parameters of patients, before and after surgery is creating demand for multiparameter patient monitoring systems.

The market growth is also supported by the increasing need for hospital transport, such as intrahospital or out-of-the-hospital transport. For special examination and therapy, hospitals require intrahospital transport, which calls for more continuous monitoring of vital signs including heart rate, blood pressure, blood oxygen saturation by pulse oximetry, and electrocardiography.

Healthcare providers are continually looking for innovative products to provide superior quality of care, which is also expected to drive the market. Mobile solutions, data integration low-acuity monitoring remain key trends to improve the cost efficiency of patient monitoring solutions. Key companies are introducing advanced products, such as integrated remote monitoring solutions with added features of greater connectivity through cloud technology and WiFi.

For instance, Radius-7 Pulse Co-Oximeters by Masimo Corp., which got U.S. FDA approval in March 2020. It is a wearable patient monitor with flexible functionality of WiFi, Bluetooth, and alarms.

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https://www.grandviewresearch.com/industry-analysis/multiparameter-patient-monitoring-systems-market

Further key findings from the study suggest:

  • The portable segment is anticipated to grow at the fastest CAGR of 6.1% from 2020 to 2027 due to growing home healthcare and easy mobility across different departments within the hospital
  • The hospital end-use segment led the market in 2019 due to high demand for modern healthcare facilities
  • North America held the maximum share of the global market in 2019 due to the availability of technologically advanced equipment and high quality of healthcare system
  • Asia Pacific is estimated to be the fastest-growing regional market during the forecast years due to increasing awareness about technologically advanced monitoring systems

Biological Safety Cabinets Market Size Worth 282.1 Million By 2027

The global biological safety cabinets market size is expected to reach USD 282.1 million by 2027, registering a CAGR of 7.5%, according to a new report by Grand View Research, Inc. Technological advancements due to a rise in laboratory procedures performed that play a crucial role in the safety of personnel, product, and environment, have propelled the market growth. The introduction of smart biosafety cabinets, such as PureLogic+ manufactured by Labconco Inc., with new features and adjustable accessories is playing a crucial role in the growth of the market.

To improve the safety, efficacy, and maintenance, NCBI launched a biological safety cabinet certification program in 2016, which certifies the design, construction, performance, and field parameters of the cabinets. There are various initiatives like the biosafety management programs taken up by the government and private companies that include complete investigation of the cabinets.

Factors like the favorable regulations, increasing prevalence of communicable diseases and rising number of pharmaceutical companies and their R&D activities are anticipated to boost the market growth. However, high product costs and introduction of alternative containment cabinets like the compounding isolators are likely to restrain the market growth.

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https://www.grandviewresearch.com/industry-analysis/biological-safety-cabinets-market

Further key findings from the study suggest:

  • Class II type emerged as the largest product segment in 2019 owing to great efficiency and result delivery of these products
  • The type A of Class II segment is projected to register the highest CAGR over the forecast period as they offer advantages, such as improved safety
  • Pharmaceuticals and biopharmaceutical companies had the highest market share due to focus on R&D and innovation by these companies
  • For instance, in 2018, NuAire launched LabGard ES NU 540, a series of advanced type II biological safety cabinets featuring AeroMax control system and HEPEX zero leak airflow system with dynamic air barrier that allows the technicians to work with precision and efficiency without the risk of contamination