Biosimilars Market Size Worth $61.47 Billion By 2025

The global biosimilars market size is expected to reach a value of USD 61.47 billion by 2025, according to a new report by Grand View Research, Inc. It is expected to expand at a CAGR of 34.2% over the forecast period. Major biological drugs are approaching the patent cliff. This is the most significant driving factor for the market. For instance, Roche’s MabThera/Rituxan (rituximab), a monoclonal antibody biologics was approved by the U.S. Food and Drug Administration (FDA) in November 1997 and its U.S. patent expired in September 2016. Several companies such as Amgen, Boehringer Ingelheim, and Pfizer are focusing on the development of biosimilar drugs of rituximab.

Furthermore, the lower cost of biosimilars compared to patented biologics and positive outcomes in clinical trials are expected to boost market growth. For instance, in July 2016; Allergan plc and Amgen stated results from a Phase 3 clinical study of ABP 980 compared with trastuzumab, a recombinant DNA-derived humanized monoclonal antibody. This drug was approved for early and metastatic breast cancer and metastatic gastric cancer in many regions. Currently, there is a boom in the pharmaceutical industry for the development of biosimilar drugs, which is a cost-saving alternative to biologic drugs. Amgen Inc.; Sandoz International GmbH; Teva Pharmaceutical Industries Ltd.; Pfizer Inc.; Biocon; Samsung Bioepis; and Mylan N.V are some of the companies focusing on the development and production of biosimilars.

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https://www.grandviewresearch.com/industry-analysis/biosimilars-market

Further key findings from the report suggest:

In 2016, the recombinant non-glycosylated protein was the largest revenue-grossing segment in the biosimilars market owing to the prevalence of growth hormone deficiency and diabetes and other chronic diseases
Recombinant glycosylated protein segment is expected to grow at a significant rate during the forecast period owing to demand erythropoietin and monoclonal antibodies for the treatment of cancer and anemia
Oncology accounted for the largest share in the application segment in 2016 due to increasing adoption of low-cost biosimilar drugs for cancer treatment
Europe was the leading regional segment in terms of revenue share in 2016 owing to favorable regulatory policies
North America is expected to witness the highest CAGR during the forecast period owing to the high prevalence of chronic diseases and a rising number of drug approvals
Some of the major players are Amgen Inc.; F. Hoffmann-La Roche Ltd.; Sandoz International GmbH; Dr. Reddy’s Laboratories Ltd.; Teva Pharmaceutical Industries Ltd.; Pfizer Inc.; Samsung Bioepis; Biocon; and Mylan N.V.

Epigenetics Market Size Worth $22.05 Billion By 2025

The global epigenetics market size is expected to reach USD 22.05 billion by 2025, according to a new study by Grand View Research, Inc., progressing at a CAGR of 19.7% during the forecast period. The growing prevalence of cancer and other diseases worldwide with an epigenetic modification base is expected to drive the market during the forecast period.

Diagnostic companies are coming up with new products such as antibodies specific for the detection of modifications and new upgraded kits for easy and efficient detection of biomarkers. This is estimated to attract pharmaceutical companies to collaborate for the development of therapeutic drugs, which will work in favor of the market.

The presence of pipeline drugs and their expected commercialization is anticipated to boost the growth of the market. For instance, Ramucirumab (Cyramza) by Eli Lilly and Company was approved by the FDA for use in combination with Folfiri for the treatment of patients with metastatic colorectal cancer.

Technology advancements in the epigenetics industry are majorly focusing on the detection of methylation markers related to cancer development. For instance, Epi proLung BL Reflex Assay by Epigenomics helps in the diagnosis of lung cancer by determining methylation of SHOX2 biomarker gene.

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https://www.grandviewresearch.com/industry-analysis/epigenetics-market

Further key findings from the study suggest:

On the basis of product, reagents held the largest share in the market in 2017. They are projected to amount to approximately USD 7.06 billion by 2025 owing to increasing R&D activities in the field of epigenetics
The kits segment is expected to post a CAGR of over 20.0% due to the need for rapid and accurate detection techniques
DNA methylation, on the basis of technology, held the leading revenue share in the market in 2017, accounting for just over 47.0%. The rapid adoption of advanced techniques such as methylation-sensitive PCR (MSP) to improve diagnostics efficiency is poised to bolster the growth of the segment
North America commanded the leading position in the global arena with a share of 40.0% in 2017. The growth of the regional market can be attributed to the increasing prevalence of cancer and growing collaborations between large pharmaceutical firms for the development of improved therapeutics
Asia Pacific is estimated to register a noteworthy CAGR of 22.1% during the forecast period owing to the presence of a large target population coupled with high unmet clinical needs
Some of the major players of epigenetics market are Illumina; Abcam; Diagenode; Thermo Fisher Scientific; Merck; Zymo research; Qiagen; CellCentric Ltd; Chroma Therapeutics Ltd; Eisai Co. Ltd; Novartis International AG; Oncolys Biopharma Inc.; Syndax Pharmaceuticals, Inc.; Valirx Plc; and Sigma-Aldrich Corporation
Extensive R&D initiatives for the development of novel drugs and the presence of strong product pipeline are expected to further boost market growth over the forecast period.

In Vitro Diagnostics Market Size Worth $100.8 Billion By 2026

The global in vitro diagnostics market size is expected to reach USD 100.8 billion by 2026 registering a CAGR of 4.75%, according to a new report by Grand View Research, Inc. Favorable government regulations supporting approval process of medical devices and rising geriatric population are among the key factors driving the market. For instance, in August 2018, the central government of India amended provisions in the Fourth Schedule of Medical Devices Rule to ease the approval process for IVD devices. In July 2017, bioMerieux received an FDA approval for VITEK MS, its mass spectrometry system for rapid identification of pathogens, such as mycobacteria, molds, and Nocardia species.

In addition, various initiatives by private and public organizations are projected to fuel market growth. For instance, In July 2018, NAMSA-a Medical Research Organization-launched its “Uniquely IVD” development services to expedite the commercialization of IVD devices for global manufacturers. NAMSA is collaborating with global regulatory bodies to investigate the international regulatory framework and delivers highly reliable IVD development outputs related to clinical research initiatives, quality, and regulatory systems.

Furthermore, rising need for onsite and early diagnosis and treatment plans is anticipated to accelerate the demand for highly accessible IVD products. Rising prevalence of diseases, such as Cardiovascular Disorders (CVDs), cancer, and diabetes, are also expected to increase the demand for IVD. According to Cancer Research U.K., in 2018, about 17 million cancer cases were reported. Key companies, such as Becton, Dickinson and Company; Hologic, Inc. (Gen-Probe); bioMerieux SA; and F. Hoffmann-La Roche Ltd.; are focusing on product development, collaborations, and M&A to increase their market share and product portfolio.

For instance, in February 2018, BD announced the availability of PAXgene Blood ccfDNA tube (CE-IVD marked) used for cancer and non-invasive prenatal testing application in Switzerland and the European Economic Area. This product was developed by a joint venture of BD and Qiagen-PreAnalytiX GmbH. In addition, in September 2018, Cepheid received CE-IVD clearance for Xpert HCV VL Fingerstick used to detect and quantify HCV RNA levels from fingerstick blood sample.

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https://www.grandviewresearch.com/industry-analysis/in-vitro-diagnostics-ivd-market

Further key findings from the study suggest:

Reagent product segment held the largest market share of 64.9% in 2018 owing to the high usage of reagents in IVD testing
Molecular diagnostics is expected to witness the fastest growth over the forecast period owing to its high usage in detecting various diseases
Infectious disease application segment led the global IVD market in 2018 and is projected to maintain the dominance during the forecast period
Asia Pacific region is expected to exhibit the fastest growth from 2019 to 2026 on account of rapidly improving healthcare infrastructure and presence of large target population base