Viral Vectors & Plasmid DNA Manufacturing Market Worth $1.1 Billion By 2027

The global viral vectors & plasmid DNA manufacturing market size is expected to reach USD 1.1 billion by 2027, exhibiting a 14.52% CAGR, during the forecast period, according to a new report by Grand View Research, Inc. Currently, more than 700 cell and gene therapies are in clinical trials and vectors are used in nearly 70% of these therapies. As a result, demand for vectors has exceeded the supply rate. Thus, an increase in the number of advanced therapy-based discovery programs initiated by biotechnology and pharmaceutical companies is expected to drive investments in the market.

Current production methods for viral vectors are considered tedious, as they are only applicable for scale-out but not for scale-up. Development of a proprietary CAP-GT technology-based cell suspension system by CEVEC Pharmaceuticals GmbH has effectively addressed the challenge of scaling-up by allowing easy handling and improved efficiency of cells.

Considering growing opportunities in vector production, the Original Equipment Manufacturers (OEMs) are making focused efforts to gain a competitive advantage in the market. For example, the introduction of ready-to-run factory-in-a-box to accelerate the production of virus-based therapeutics by GE healthcare, as a solution to simplify and advance the manufacturing process.

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https://www.grandviewresearch.com/industry-analysis/viral-vector-manufacturing-market

Further key findings from the study suggest:

With high usage, attributed to its ability of high titer production and capability to induce strong humoral and T cell responses in various research applications, adenovirus held the leading viral vectors and plasmid DNA manufacturing market share in terms of revenue, in 2019
Lentivirus vector is anticipated to register the fastest CAGR over the forecast period. This can be attributed to constant growth in the lentivirus-based gene therapy pipeline program
Downstream processing held the dominant revenue share in 2019, owing to the fact that this process involves purification steps that account for the majority of the overall manufacturing cost. Employment of expensive equipment and requirement of trained personnel for product recovery has further driven revenue in the segment
Antisense and RNAi therapy production is estimated as the key application of vector manufacturing, resulting in the dominance of this segment over other applications
The high adoption rate of viruses for aptamers and oligonucleotide development in comparison to other applications has driven revenue in antisense and RNAi therapy segment
High usage of vectors for therapeutic production have contributed to the large revenue share of pharmaceutical and biopharmaceutical companies. The number of biotech companies employing vector for therapies production is anticipated to multiply over the forecast period
Presence of a substantial number of advanced therapy products in the pipeline targeting various cancer forms has accelerated revenue share of the cancer segment over the years
Given the high number of biotech entities in parts of U.S., such as in California and Massachusetts, North America has maintained its dominance in terms of revenue. In addition, the active participation of regulatory bodies in improving the regulatory scenario for the market launch of advanced therapies has facilitated the high usage of vectors in U.S.
Merck, Cobra Biologics, Novasep, and uniQure N.V., are some key participants that are geared towards capitalizing the untapped opportunities in the market

Sickle Cell Disease Treatment Market Worth $5.5 Billion by 2023

The global sickle cell disease treatment market size is expected to reach USD 5.5 billion by 2023, according to a new report by Grand View Research, Inc., exhibiting a 14.3% CAGR during the forecast period. Several factors such as increase in investments for R&D, growing target population, and favorable government initiatives are anticipated to drive the market.

Currently available treatments for sickle cell disease (SCD) usually provide symptomatic relief and palliative care. These treatment methods generally include blood transfusions, bone marrow transplant, and pharmacotherapy. Although bone marrow transplant is the only potentially curative treatment, it is recommended only to a small percentage of patients. The market has only two approved products—hydroxyurea and Endari.

High unmet medical needs, strong pipeline, and growing patient pool are key factors expected to influence market growth. In recent years, demand for cost-effective drugs and gene therapies for SCD has increased owing to the unavailability of a permanent cure and risks associated with bone marrow transplant.

Expected launch of late-stage pipeline drugs such as voxelotor, crizanlizumab, Altemia, and rivipansel is projected to drive the sickle cell disease market during the forecast period. Healthcare initiatives undertaken by respective economies are crucial for curbing the financial burden of the disease as well as for increasing access to healthcare facilities and providing various services for early diagnosis, subsequent treatment, and palliative care.

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https://www.grandviewresearch.com/industry-analysis/sickle-cell-disease-treatment-market

Further key findings from the report suggest:

Currently, 20 to 25 million people worldwide are reportedly living with sickle cell disease and about 300,000 infants are born annually with the disease
The U.S. dominated the global market and is projected to maintain its position through 2023, owing to rise in incidence of diseases and launch of promising pipeline candidates
Among treatments, blood transfusion held the largest share in 2017, followed by pharmacotherapy. However, it is anticipated that pharmacotherapy will lead the market by 2023, supported by a strong pipeline and several promising drug launches
Emmaus Medical, Global Blood Therapeutics, bluebird bio, Pfizer, and Novartis are some of the key players operating in this market
Emmaus Medical is projected to dominate the SCD pharmaceutical market in 2023, supported by strong sales of Endari
Currently, 37 pipeline drugs are in various clinical development stages and significant sales contribution is expected from promising candidates such as voxelotor (Global Blood Therapeutics), crizanlizumab (Novartis), Altemia (Sancilio), and rivipansel (Pfizer).

X-ray Systems Market Size Worth $10.43 Billion By 2025

The global x-ray systems market size is expected to reach USD 10.43 billion by 2025, according to a new report by Grand View Research, Inc., registering a 2.9% CAGR during the forecast period. Rising investments in medical technology, increasing R&D activities, and a surge in product launches are key factors driving market growth.

Prominent modalities include radiography, fluoroscopy, and computed radiography. Computed radiography systems are the most preferred systems, as they provide sharp images in a shorter time. Moreover, the imaging plates can be reused. Fluoroscopy is also gaining prominence in developed countries such as the U.S. and Canada.

X-ray systems can be stationary or portable. Even the stationary systems dominated the market in 2017 in terms of revenue, the portable kind are poised to witness faster growth. Stationary radiography systems have significant demand in developing countries where adaption to new technology is slow. Portable systems are preferred over stationary variants due to their mobility, which makes them more convenient and flexible for use.

Some of the key players in this market are Koninklijke Philips N.V.; GE Healthcare; Hitachi, Ltd.; Shimadzu Corporation, Fujifilm Medical Systems; Siemens Healthineers; Canon Medical Systems Corporation; Carestream Health; Hologic, Inc.; and Biosign. Expansion of regional and service portfolios and mergers and acquisitions are some of the leading strategic undertakings adopted by these players. For instance, in December 2016, Hitachi acquired Kurt & Kurt, a medical diagnostic system provider, to expand its businesses in Turkey.

Click the link below:
https://www.grandviewresearch.com/industry-analysis/x-ray-systems-market

Further key findings from the report suggest:

The global X-ray systems market was valued at USD 8.3 billion in 2017 and is expected to at a modest pace over the forecast period
Based on type, digital systems are anticipated to grow at the fastest rate as analog systems fade out
By modality, the computed radiography segment was valued at USD 2.9 billion in 2017, emerging as the market leader. Fluoroscopy will register the fastest growth over the forecast period
While hospitals enjoy the dominant share on the basis of end use, the diagnostic centers segment is anticipated to register a CAGR of 3.6% from 2018 to 2025

North America Extremity Tissue Expanders Market Worth $79.2 Million By 2025

The North America extremity tissue expanders market size is expected to reach USD 79.2 million by 2025, according to a new report by Grand View Research, Inc., exhibiting a 3.4% CAGR during the forecast period. Increase in number of road accidents and burn-related cases is driving the market. Rising incidence of congenital deformity is also anticipated to boost market demand.

As stated by the Centers for Disease Control and Prevention (CDC) in 2014, annually, around 40 million people in U.S. visit the emergency room because of trauma injuries including burns and severe fractures. Thus, demand for extremity tissue expanders for treatment of patients with severe hand and/or leg injuries resulting from road accidents or trauma is expected to increase in future.

Use of extremity tissue expanders is gaining popularity and has become the preferred treatment option for many congenital defects in adults as well as children. In addition, technological advancements in this field are expected to drive the market. For instance, advanced soft tissue expanders facilitate early closure of surgical or traumatic wounds without the need for further complicated plastic surgery.

Click the link below:
https://www.grandviewresearch.com/industry-analysis/north-america-extremity-tissue-expanders-market

Further key findings from the study suggest:

Round shaped expanders held the largest share in 2017 owing to the various benefits associated with this shape as well as its wide availability with major companies
Anatomical shaped expanders contributed to a limited revenue share in 2017 owing to fewer products available with key manufacturers
Hospitals accounted for the largest market share in 2017 because they are considered to be the primary point-of-care for preliminary treatment
Burn centers are projected to show significant growth over the forecast period due to surge in burn-related injuries
U.S. held the dominant share in 2017 due to increase in number of reconstruction procedures, which are undertaken to improve patients’ physical appearance and self-confidence
Canada is anticipated to witness the highest growth over the forecast period owing to presence of a strong distribution network of a large number of medical devices manufacturers and a developed economy
Some of the major companies of the market are Mentor Worldwide LLC; Sientra, Inc.; PMT Corporation; Allergan; and KOKEN CO., LTD.

Endpoint Security Market Size Worth $27.05 Billion By 2024

The endpoint security market size is expected to reach USD 27.05 billion by 2024, according to a new report by Grand View Research, Inc. The endpoint security market is expected to witness a substantial growth over the forecast period, due to the increasing deployment of various security solutions with rising security risks across several applications including BFSI, IT & telecom, and retail.

The rising number of enterprise endpoints and mobile devices having access to critical enterprise data have created a huge demand for endpoint security solutions in the market, which is anticipated to drive the market.

Moreover, emerging trend of virtualization is projected to affect endpoint security. Virtualization separates physical systems into several virtual machines, which will require similar endpoint protection as physical servers. Hence, escalating the demand for more efficient and comprehensive solutions over the forecast period.

Several companies in the industry are spending on different technologies to improve capabilities, secure internet protocols, test software and analyze vulnerabilities. The evolution of cloud storage has increased the adoption of cloud-based security services; the as significant amount of data is stored in one place. This has led to increased threat of data breaches and enforcement of various regulations to curb the risk of placing the data on the cloud.

Click the link below:
https://www.grandviewresearch.com/industry-analysis/endpoint-security-market

Further key findings from the report suggest:

The mobile device security segment witnessed revenue share of over 17% in 2015, which is anticipated to grow at a CAGR of nearly 16% over the forecast period. The increasing adoption of BYOD trend have led the employees in organizations to access corporate data on their personal mobile devices. However, it creates security challenges, which requires advanced endpoint security solutions to safeguard sensitive business information resulting in high demand.
Enterprises dominated the market in 2015, and is estimated to grow at a CAGR of over 13% from 2016 to 2024. SMBs are also anticipated to witness substantial growth over the forecast period due to the rising adoption such safety solutions to prevent crucial information. Organizations of all sizes are transitioning their business-critical operations and workloads to cloud computing to decrease the burden on their IT support staff, reduce costs and provide advanced services. The increasing adoption of cloud technology have led security vendors to develop cloud-based security solutions on a large scale.
IT & Telecom industry dominated the market with the revenue share of nearly 25% in 2015 and is anticipated to witness significant growth over the next eight years. The industry has evolved through significant expansion phase and have stringent legal and information security requirements. Further, rising acceptance of BYOD trend is anticipated to drive the industry demand.
Moreover, the BFSI sector offers substantial potential for the market as it is continuously visualizing the regional; instability, terrorism, physical risks, criminal networks and modern threats originating from cyber sabotage and opaque sources. The rising regulation in the finance sector is further contributing towards the industry growth.
The North America is estimated to dominate the market with a share of over 32% in 2015 growing at a CAGR of nearly 11% over the next eight years. Asia Pacific regional market accounted for over 19.0% of the global market share in 2015 and is expected to grow with a CAGR of 13.2% over the next eight years. Stringent regulations across Asia Pacific are expected to fuel the demand for efficient endpoint security solutions driving the demand in this region. Countries including China, India, Malaysia and Australia are investing heavily in endpoint security to fight against cyber threats and attacks.
The key industry participants include Microsoft Corporation, Kaspersky Labs, Panda Security SL, Symantec Corporation, Sophos Ltd, Cisco, Bitdefender, ESET, IBM Corporation, F-Secure, Intel Security Inc. (McAfee) and Trend Micro Incorporated. The vendors involve in frequent merger & acquisitions to increase their geographical presence and product portfolio to gain competitive advantage.

Cable Management System Market Size Worth $26.48 Billion By 2025

The global cable management system market size is poised to reach USD 26.48 billion by 2025, according to a new study by Grand View Research, Inc., progressing at a CAGR of 8.2% during the forecast period. Growing demand for cable management systems in the IT & telecommunication industry is projected to augment the market.

Cable management products help in handling cabling systems in residential and commercial buildings to manage cable connections during pre-construction as well as post construction. Numerous components of cable management systems are used in the construction industry, such as floor ducts & boxes, cable glands & connectors, electrical raceways, trays & ladders, and electrical conduit systems. Surging demand for better infrastructure and rapid industrialization in developing economies are driving the cable management system market.

Government initiatives for time-bound creation of excellent infrastructure in developing countries are boosting the growth of the construction sector, which in turn is fueling the demand for cable management systems. Using these systems minimize the risk of cables being disconnected and also protect them from damages caused due to stretching or harsh environment conditions.

Stringent legal and regulatory standards have compelled manufacturers to develop durable and flexible management systems. This is further anticipated to boost the demand for cable management systems over the forecast period. Growing demand for metallic cable trays in industrial and commercial applications is estimated to stoke market growth.

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https://www.grandviewresearch.com/industry-analysis/cable-management-system-market

Further key findings from the report suggest:

Cable management systems find applications in the oil & gas industry due to properties such as ability to perform in harsh environments, reliability, high insulation, and high resistance to chemicals
PVC plastic materials are widely used in the oil & gas industry owing to their high acid-resistant capability. Heat shrinks insulation cables in case of fire, due to which they are primarily used in the manufacturing of cable ducts, cable trays, and cable trunks that are installed in oil & gas plants
North America is expected to dominate the market through 2025, accounting for over 32.0% of the overall revenue
Surging demand for data communication cables for transmission of signals is likely to escalate the need for cable trays and cable trunks in regions such as China, Japan, India, and other developing countries
Key industry participants include ABB Ltd.; Atkore International Holdings Ltd.; Chatsworth Products, Inc.; Eaton Corporation; Legrand SA; and Enduro Composites, Inc.

Brushless DC Motor Market Worth $27.2 Billion By 2027

The global brushless DC motor market size is expected to reach USD 27.2 billion by 2027, registering a CAGR of 6.6% over the forecast period, according to a study conducted by Grand View Research, Inc. These motors are thermally resistant, require low maintenance, and operate at low temperatures, eliminating any threat of sparks.

Low maintenance costs, retrofitting of existing air, high-efficiency at lower costs, and the rising adoption of electric vehicles are some of the key factors driving their growth over the forecast period. The emergence of sensor-less controls for brushless DC type is likely to boost the durability and reliability of the product, thereby reducing the number of mechanical misalignments, electrical connections, as well as the weight and size of the end product. These factors are further estimated to drive market growth over the forecast period.

Furthermore, production of vehicles, globally, in order to cope up with the rising demand for vehicles internationally is anticipated to further impact market growth. Brushless DC motors are extensively used in motorized vehicle applications such as in sunroof systems, motorized seats, and adjustable mirrors. Additionally, these powertrains are extensively being preferred for performance applications in vehicles such as chassis fittings, power-train systems, and safety fittings owing to simple structure, less maintenance requirements, and extended operational life. Increasing product adoption by the automobile industry in numerous vehicles for multiple applications is anticipated to drive the growth of the market tremendously over the forecast period.

Electric vehicles extensively use brushless DC motors in mechatronic systems primarily in batteries for accumulators and power electronic converters. This is owing to advantages such as high operating speed, compact size, and quick response time. Production of electric vehicles is on rise globally supported by government initiatives to encourage use of non-conventional fuels and effectively reduce the adverse impacts of carbon emissions. The increasing electric vehicle production is anticipated to directly impact the demand for brushless motors over the forecast period.

Click the link below:
https://www.grandviewresearch.com/industry-analysis/brushless-dc-motors-market

Further key findings from the report suggest:

On account of benefits including durability and less maintenance, the brushless DC motor captured a substantial market share in 2019, a trend that is anticipated to continue over the forecast period.
The 0 – 750 Watt segment is expected to witness rapid growth from 2020 to 2027, which can be primarily ascribed to their extensive applications in numerous motorized vehicles and household devices applications
Motorized vehicles extensively use the powertrain for variety of applications. Increased production of automobiles and e-vehicles across the globe is anticipated to positively impact the growth of the segment over the forecast period
The industrial machinery segment held more than 20% of the global brushless DC motor market share in 2019. Numerous industrial machines deploy the motor owing to advantages offered such as high efficiency, low power consumption, and low maintenance costs
Asia Pacific is expected to emerge as the fastest-growing regional market, whilst registering a CAGR 8.0% over the forecast period. Increasing industrialization in developing nations such as China, India, and South Korea has fueled the regional market
The key players capturing major market share include ABB Ltd; Ametek Inc.; Johnson Electric; and Nidec Motor Corporation. Numerous companies are focusing on developing low-maintenance and eco-friendly products in order to gain a competitive edge.

Connected Enterprise Market Size To Reach $1.94 Trillion By 2025

The global connected enterprise market size is expected to reach USD 1.94 trillion by 2025, according to a new report by Grand View Research, Inc. The increasing need for automation and the proliferation of connected devices is providing new growth avenues for the connected enterprise market.

Enterprises are moving toward digital technologies to transform their business operations, improve customer experiences, and rapidly respond to emerging threats and opportunities. Industry collaborations with connected technology are gaining prominence for improving agility, productivity, and business process management. Although the Internet-of-Things (IoT) and connected technologies are becoming adept, several organizations have not included their collaboration with smart technologies in business strategies.

The implementation of intelligent networks has improved the optimization of assets including equipment reliability, and energy usage, and has expanded the capacity of existing assets. Enterprises are integrating people, tools, processes, and platforms comprising infrastructure and applications to disrupt business productivity with next-generation solutions.

Moreover, organizations are looking for innovative ways to differentiate themselves from their competitors and overcome threats from new entrants. Connected solutions are increasingly adopted for generating new revenue streams and improving profit margins. These solutions help enterprises in increasing their operational efficiency by enabling real-time monitoring of assets. However, fragmented technology standards and growing security concerns are expected to deter industry growth.

Click the link below:
http://www.grandviewresearch.com/industry-analysis/connected-enterprise-market

Further key findings from the report suggest:

Customer experience management is expected to be the fastest-growing segment owing to its transition from being transactional to a more interactive and informative solution
The managed services segment is expected to grow at a CAGR of over 35% from 2016 to 2025. due to the increasing need for outsourcing IoT-related capabilities
The device management platform is anticipated to account for over 25% revenue share by 2025; the need to drive connected products assessment, reduce operational costs, and improve service quality is propelling the demand for a device management platform
The healthcare sector is expected to reach a valuation of over USD 150 billion by 2025 on account of its transition from providing provider-centric to patient-centric solutions
The Asia Pacific region is expected to be the fastest-growing regional market as the enterprises in the region are deploying connected infrastructure in new areas to improve their revenues.
The key industry players include IBM Corporation, Rockwell Automation, Inc., IBM Corporation, Honeywell International, Inc., and PTC Inc.

Non-Invasive Brain Trauma Monitoring Devices Market Worth $15.1 Billion By 2024

The global non-invasive brain trauma monitoring devices market is expected to reach USD 15.12 billion by 2024, according to a new report by Grand View Research, Inc. The rising burden of Traumatic Brain Injuries (TBI) is a leading cause of neurodegenerative disorders such as Alzheimer’s and Parkinson’s disease. As a result, there are numerous initiatives taken at the regional and global levels to create awareness, which facilitated a heavy diagnosis rate, thus governing the growth of non-invasive brain trauma monitoring devices.

Technological advancements in this field are connected with accuracy, portability, and affordability, which are supporting the industry growth. For instance, recently available non-invasive intracranial pressure monitors, such as Transcranial Doppler (TCD), are accurate in positioning and creating a better pressure gradient and also bringing in more accuracy in the treatment.

The Minimally Invasive Surgeries (MIS) are less traumatic to patients and facilitate faster recovery with minimum complications. In minimally invasive neurological surgeries, non-invasive brain trauma monitoring devices play a critical role. Thus, the increasing volume of MIS is driving the industry’s growth.

The key target population in this industry includes people above 60 years. This section of the population is at a greater risk for TBIs and their co-morbidities. The global geriatric population is on arise and is a vital driver for this industry.

Click the link below:
http://www.grandviewresearch.com/industry-analysis/non-invasive-brain-trauma-monitoring-devices-market

Further key findings from the study suggest:

Monitoring devices that include intracranial pressure monitors, MRI scanners, CT scanners, PET scanners, EEG, and MEG held a substantial share of around 60.0% in 2015. The high costs associated with this equipment and the increasing usage of these devices governed the growth of this segment.
The consumables sub-segment in the product segment is anticipated to witness lucrative growth over the forecast period. The repeat purchase of consumables and regular maintenance activities are expected to spur the demand for these products.
The market on the basis of end-use is segmented into hospitals, neurological centers, and other settings. The hospital segment dominated the end-use segment with over 75.0% of the revenue. The greater volume of surgeries performed in hospitals contributed to its growth.
On the contrary, neurological centers are expected to grow at a sturdy rate over the forecast period. The availability of specialized staff and advanced methodologies are likely to boost the demand for this segment.
North America dominated the non-invasive brain trauma monitoring devices market in 2015. The advanced healthcare system, high awareness level, and well-planned reimbursement policies helped this market to grow in this region. However, Asia Pacific is anticipated to witness significant growth over the forecast period.
Some key players operating in this industry include Natus Medical, Inc., Nihon Kohden Corporation, Philips Healthcare, GE Healthcare, Advanced Brain Monitoring, CAS Medical Systems, Inc., Siemens, Compumedics Ltd., Medtronic Plc., and Integra LifeSciences. New product launches, co-developments, and acquisitions are the key initiatives in this industry.
For instance, in January 2013, Natus Medical acquired Astro-Med’s products included in monitoring and neurodiagnostic products. This acquisition helped the company to widen the portfolio of EEG systems.

Molecular Cytogenetics Market Size Worth $3.8 Billion By 2025

The global molecular cytogenetics market size is expected to reach USD 3. 8 billion by 2025, according to a new report by Grand View Research, Inc., exhibiting a 10.4% CAGR during the forecast period. Mapping of human genome, coupled with continuous technological advancements in cytogenetic techniques, has enabled researchers to gain insight into the disease-causing mechanism at a genomic as well as the cellular level. Development in molecular technologies has helped in bridging the gap between molecular biology and cytogenetics, which was not possible using conventional cytogenetic techniques.

There is a continuous growth in awareness, and consequent adoption, of genetic tests for disease prognosis. These tests also help in designing further treatment regimes for widespread chromosomal abnormalities. This is sure to boost the market growth.

Incorporation of high throughput sequencers in the cytogenetic analysis is expected to significantly enhance the market growth in the coming years. A number of researchers and scientists have begun converging cytogenetics laboratories with NGS as they complement each other. Hence, with an exponential decline in sequencing prices, this market is expected to grow at a lucrative pace.

However, ambiguous regulatory and reimbursement scenario in certain regions pertaining to the implementation of genetic tests is expected to hamper the adoption of molecular cytogenetic techniques to a certain extent.

Click the link below:
https://www.grandviewresearch.com/industry-analysis/molecular-cytogenetics-market

Further key findings from the report suggest:

Oncology held the largest share in the market in 2016 owing to the ability of CGH technology to facilitate in-depth studies for cancer etiology
The use of molecular cytogenetics in personalized medicine development is expected to grow lucratively during the forecast period. This is majorly due to a continuous shift toward targeted therapies for effective disease management
The requirement of consumables in the entire cytogenetics process is attributive for the largest share of this product category
Ongoing research projects for developing a treatment regimen of different genetic conditions have allowed clinical and research laboratories to gain a significant share in the market
Pharmaceutical and biotech companies are expected to be a key source of revenue in the coming years. This is mainly because a number of pharmaceutical companies have expanded their business in the field of personalized medicine
Illumina, Inc.; Agilent Technologies, Inc.; Abbott; Bio-Rad Laboratories, Inc.; and Oxford Gene Technology are some prominent companies in the market. They are involved in the development and commercialization of cytogenetics techniques
Some major service providers are Weill Cornell Medicine; WiCell Research Institute, Inc.; ARUP Laboratories; and Integrated Systems Engineering S.r.l.